MeSH Browser

MeSH Heading: Cerebroside-Sulfatase
Tree Number(s): D08.811.277.352.827.070.250
Unique ID: D002553
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D002553
Annotation: /defic: consider also LEUKODYSTROPHY, METACHROMATIC
Scope Note: An enzyme that catalyzes the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase A, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.8.
Entry Term(s): Arylsulfatase A; Sulfatidate Sulfatase
CAS Type 1 Name: Cerebroside-3-sulfate 3-sulfohydrolase
Previous Indexing: Arylsulfatases (1975); Sulfatases (1972-1974)
See Also: Leukodystrophy, Metachromatic
Public MeSH Note: 87; was see under SULFATASES 1976-86
History Note: 87(76); was see under SULFATASES 1976-86
Date Established: 1987/01/01
Date of Entry: 1975/07/25
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Cerebroside-Sulfatase MeSH Descriptor Data 2024