MeSH Browser

MeSH Heading: Chimerin 1
Tree Number(s): D12.644.360.325.150.100.200; D12.776.476.325.150.100.200; D12.776.631.124.200
Unique ID: D020848
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020848
Scope Note: A GTPase activating protein that is specific for RAC GTP-BINDING PROTEINS. It is expressed primarily in the brain and may be involved in signal transduction. The alternatively spliced form of CHIMERIN 1 (alpha-2 Chimerin) contains an additional src homology domain and is expressed in both the brain and testes.
Entry Term(s): Chimaerin 1; alpha-1 Chimaerin; alpha-1 Chimerin; alpha-2 Chimaerin; alpha-2 Chimerin; alpha-Chimaerin; alpha-Chimerin; alpha1-Chimaerin; arhGAP2 Protein; n-Chimaerin; n-Chimerin; rhoGAP2 Protein
Previous Indexing: Nerve Tissue Proteins (1991-1999)
Public MeSH Note: 2000; N-CHIMAERIN (now CHIMERIN 1) was indexed under NERVE TISSUE PROTEINS 1990-1999; ALPHA1-CHIMAERIN was indexed under PROTEINS 1996-1999
History Note: 2000; use CHIMERIN 1 (NM) 1990-1999; for ALPHA1-CHIMAERIN use GTPASE-ACTIVATING PROTEINS (NM) 1996-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intracellular Signaling Peptides and Proteins [D12.644.360]
    - GTP-Binding Protein Regulators [D12.644.360.325]
      - GTPase-Activating Proteins [D12.644.360.325.150]
        
        Chimerin Proteins [D12.644.360.325.150.100]
        
        Chimerin 1 [D12.644.360.325.150.100.200]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - GTP-Binding Protein Regulators [D12.776.476.325]
      - GTPase-Activating Proteins [D12.776.476.325.150]
        
        Chimerin Proteins [D12.776.476.325.150.100]
        
        Chimerin 1 [D12.776.476.325.150.100.200]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Nerve Tissue Proteins [D12.776.631]
    - Chimerin Proteins [D12.776.631.124]
      - Chimerin 1 [D12.776.631.124.200]

Chimerin 1 Preferred

Concept UI: M0328168
Scope Note: A GTPase activating protein that is specific for RAC GTP-BINDING PROTEINS. It is expressed primarily in the brain and may be involved in signal transduction. The alternatively spliced form of CHIMERIN 1 (alpha-2 Chimerin) contains an additional src homology domain and is expressed in both the brain and testes.
Terms: Chimerin 1 Preferred Term
Term UI T358168
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); alpha-1 Chimerin
Term UI T362071
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); arhGAP2 Protein
Term UI T362072
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); rhoGAP2 Protein
Term UI T362073
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); alpha-Chimaerin
Term UI T362074
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); alpha-Chimerin
Term UI T362070
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); alpha-1 Chimaerin
Term UI T362078
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); alpha1-Chimaerin
Term UI T186263
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); n-Chimerin
Term UI T203776
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); n-Chimaerin
Term UI T203777
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Chimaerin 1
Term UI T362075
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000)

alpha-2 Chimerin Narrower

Chimerin 1 MeSH Descriptor Data 2024