MeSH Browser

MeSH Heading: Creatine Kinase
Tree Number(s): D08.811.913.696.640.150
Unique ID: D003402
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003402
Scope Note: A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.
Entry Term(s): ADP Phosphocreatine Phosphotransferase; ATP Creatine Phosphotransferase; Creatine Phosphokinase; Macro-Creatine Kinase
Related Numbers: 9001-15-4; EC 2.7.3.2
CAS Type 1 Name: ATP:creatine N-phosphotransferase
NLM Classification #: QU 141
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0005293
Related Numbers: 9001-15-4; EC 2.7.3.2
Scope Note: A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.
Terms: Creatine Kinase Preferred Term
Term UI T009895
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1966); ADP Phosphocreatine Phosphotransferase
Term UI T009894
Date06/29/1983
LexicalTag NON
ThesaurusID UNK (19XX); ATP Creatine Phosphotransferase
Term UI T009897
Date03/13/1991
LexicalTag NON
ThesaurusID NLM (1992); Creatine Phosphokinase
Term UI T009896
Date03/29/1974
LexicalTag NON
ThesaurusID UNK (19XX)

Creatine Kinase MeSH Descriptor Data 2024