MeSH Browser

MeSH Heading: Cytotoxins
Tree Number(s): D27.888.569.213
Unique ID: D003603
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003603
Annotation: /antag permitted but consider also ANTITOXINS; coordinate with source of cytotoxin
Scope Note: Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
Entry Term(s): Cytolysins; Cytotoxic Agent; Cytotoxic Agents; Cytotoxin
Previous Indexing: Cytotoxicity Tests, Immunologic (1973-1977); specific cell (1966-1977); Toxins (1966-1977)
See Also: Antineoplastic Agents; Cytostatic Agents
Public MeSH Note: 78
History Note: 78
Date Established: 1978/01/01
Date of Entry: 1977/04/22
Revision Date: 2021/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0005633
Scope Note: Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
Terms: Cytotoxins Preferred Term
Term UI T010488
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1978); Cytotoxin
Term UI T001008518
Date02/24/2020
LexicalTag NON
ThesaurusID NLM (2021); Cytotoxic Agents
Term UI T666720
Date02/21/2006
LexicalTag NON
ThesaurusID NLM (2007); Cytotoxic Agent
Term UI T001008519
Date02/24/2020
LexicalTag NON
ThesaurusID NLM (2021)

Cytotoxins MeSH Descriptor Data 2024