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Epoprostenol MeSH Descriptor Data 2023


MeSH Heading
Epoprostenol
Tree Number(s)
D10.251.355.255.550.550.500
D23.469.050.175.725.550.500
Unique ID
D011464
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011464
Scope Note
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
Entry Term(s)
Epoprostanol
Epoprostenol Sodium
Epoprostenol Sodium Salt, (5Z,9alpha,11alpha,13E,15S)-Isomer
Flolan
Prostacyclin
Prostaglandin I(2)
Prostaglandin I2
Veletri
Pharm Action
Antihypertensive Agents
Platelet Aggregation Inhibitors
Registry Number
DCR9Z582X0
Related Numbers
35121-78-9
4K04IQ1OF4
CAS Type 1 Name
Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (5Z,9alpha,11alpha,13E,15S)-
Previous Indexing
Prostaglandins (1966-1977)
Public MeSH Note
1991; see PROSTAGLANDINS X 1978-1990; for PROSTACYCLIN see PROSTACYCLINS 1978-1993; for PROSTAGLANDIN I2 see PROSTAGLANDINS I2 1982-1993; for PROSTAGLANDIN X see PROSTAGLANDINS X 1991-1993
History Note
1991 (1978); use PROSTAGLANDINS X 1978-1990; for PROSTACYCLIN use PROSTACYCLINS 1978-1993; for PROSTAGLANDIN I2 use PROSTAGLANDINS I2 1982-1993; for PROSTAGLANDIN X use PROSTAGLANDINS X 1991-1993
Date Established
1984/01/01
Date of Entry
1977/05/23
Revision Date
2018/03/01
Epoprostenol Preferred
Veletri Narrower
Epoprostenol Sodium Narrower
Flolan Narrower
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