MeSH Browser

MeSH Heading: Filaggrin Proteins
Tree Number(s): D12.776.157.125.750.250; D12.776.631.658.500
Unique ID: D000091344
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000091344
Scope Note: S100 proteins that aggregate KERATINS. Filaggrin precursor proteins are localized in keratohyalin granules and processed into individual functional filaggrin molecules during terminal epidermis differentiation. Mutations in fillagrins are associated with ICHTHYOSIS VULGARIS.
Entry Term(s): Filaggrin; Filaggrin Protein; Profilaggrin; Stratum Corneum Basic Protein; Stratum Corneum Basic Protein Precursor
Registry Numbers: 0
Previous Indexing: Intermediate Filament Proteins (1982-2021)
Public MeSH Note: 2022; FILAGRIN was indexed under INTERMEDIATE FILAMENT PROTEINS 1984-2021; and under PROTEINS 1981-1983
History Note: 2022(1981)
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2023/06/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000748545
Registry Numbers: 0
Scope Note: S100 proteins that aggregate KERATINS. Filaggrin precursor proteins are localized in keratohyalin granules and processed into individual functional filaggrin molecules during terminal epidermis differentiation. Mutations in fillagrins are associated with ICHTHYOSIS VULGARIS.
Terms: Filaggrin Proteins Preferred Term
Term UI T001106507
Date05/17/2021
LexicalTag NON
ThesaurusID NLM (2022); Filaggrin Protein
Term UI T001106508
Date05/17/2021
LexicalTag NON
ThesaurusID NLM (2022); Filaggrin
Term UI T001106509
Date05/17/2021
LexicalTag NON
ThesaurusID NLM (2022); Stratum Corneum Basic Protein
Term UI T001106510
Date05/17/2021
LexicalTag NON
ThesaurusID NLM (2022)

Filaggrin Proteins MeSH Descriptor Data 2025