MeSH Browser

MeSH Heading: G Protein-Coupled Inwardly-Rectifying Potassium Channels
Tree Number(s): D12.776.157.530.400.600.450.500; D12.776.543.550.450.750.450.500; D12.776.543.585.400.750.450.500
Unique ID: D051676
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051676
Scope Note: A family of inwardly-rectifying potassium channels that are activated by PERTUSSIS TOXIN sensitive G-PROTEIN-COUPLED RECEPTORS. GIRK potassium channels are primarily activated by the complex of GTP-BINDING PROTEIN BETA SUBUNITS and GTP-BINDING PROTEIN GAMMA SUBUNITS.
Entry Term(s): G Protein-Activated Potassium Channels; G Protein-Coupled Inwardly-Rectifying Potassium Channel 1; G Protein-Coupled Inwardly-Rectifying Potassium Channel 2; G Protein-Coupled Inwardly-Rectifying Potassium Channel 3; G Protein-Coupled Inwardly-Rectifying Potassium Channel 4; GIRK Potassium Channels; GIRK1 Potassium Channel; GIRK2 Potassium Channel; GIRK3 Potassium Channel; GIRK4 Potassium Channel; Kir3 Potassium Channels; Kir3.1 Potassium Channel; Kir3.2 Potassium Channel; Kir3.3 Potassium Channel; Kir3.4 Potassium Channel
Public MeSH Note: 2006; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS was indexed under POTASSIUM CHANNELS, INWARDLY RECTIFYING 2005, & under POTASSIUM CHANNELS 1995-2004, & under MEMBRANE PROTEINS 1993-1994; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNEL 1, G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNEL 2, G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNEL 3, & G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNEL 4 were indexed under POTASSIUM CHANNELS, INWARDLY RECTIFYING 2004-2005
History Note: 2006(1993)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Channels [D12.776.157.530.400]
        
        Potassium Channels [D12.776.157.530.400.600]
        
        Potassium Channels, Inwardly Rectifying [D12.776.157.530.400.600.450]
        
        G Protein-Coupled Inwardly-Rectifying Potassium Channels [D12.776.157.530.400.600.450.500]
        
        Kir5.1 Channel [D12.776.157.530.400.600.450.525]
        
        KATP Channels [D12.776.157.530.400.600.450.550]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Ion Channels [D12.776.543.550.450]
        
        Potassium Channels [D12.776.543.550.450.750]
        
        Potassium Channels, Inwardly Rectifying [D12.776.543.550.450.750.450]
        
        G Protein-Coupled Inwardly-Rectifying Potassium Channels [D12.776.543.550.450.750.450.500]
        
        Kir5.1 Channel [D12.776.543.550.450.750.450.525]
        
        KATP Channels [D12.776.543.550.450.750.450.550]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Channels [D12.776.543.585.400]
        
        Potassium Channels [D12.776.543.585.400.750]
        
        Potassium Channels, Inwardly Rectifying [D12.776.543.585.400.750.450]
        
        G Protein-Coupled Inwardly-Rectifying Potassium Channels [D12.776.543.585.400.750.450.500]
        
        Kir5.1 Channel [D12.776.543.585.400.750.450.525]
        
        KATP Channels [D12.776.543.585.400.750.450.550]

G Protein-Coupled Inwardly-Rectifying Potassium Channels Preferred

G Protein-Coupled Inwardly-Rectifying Potassium Channel 2 Narrower

G Protein-Coupled Inwardly-Rectifying Potassium Channel 1 Narrower

G Protein-Coupled Inwardly-Rectifying Potassium Channel 3 Narrower

G Protein-Coupled Inwardly-Rectifying Potassium Channel 4 Narrower

G Protein-Coupled Inwardly-Rectifying Potassium Channels MeSH Descriptor Data 2024