MeSH Browser

MeSH Heading: Histidine Ammonia-Lyase
Tree Number(s): D08.811.520.232.400.500
Unique ID: D006638
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006638
Annotation: /defic: consider also histidinemia (AMINO ACID METABOLISM, INBORN ERRORS)
Scope Note: An enzyme that catalyzes the first step of histidine catabolism, forming UROCANIC ACID and AMMONIA from HISTIDINE. Deficiency of this enzyme is associated with elevated levels of serum histidine and is called histidinemia (AMINO ACID METABOLISM, INBORN ERRORS).
Entry Term(s): Histidase; Histidinase; Histidine Deaminase; Histidine alpha-Deaminase
Registry Number: EC 4.3.1.3
Related Numbers: 9013-75-6
CAS Type 1 Name: L-Histidine ammonia-lyase
Public MeSH Note: 98; see HISTIDASE 1991-97, see AMMONIA-LYASES 1973-90
History Note: 98(73)
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2006/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0010399
Registry Number: EC 4.3.1.3
Related Numbers: 9013-75-6
Scope Note: An enzyme that catalyzes the first step of histidine catabolism, forming UROCANIC ACID and AMMONIA from HISTIDINE. Deficiency of this enzyme is associated with elevated levels of serum histidine and is called histidinemia (AMINO ACID METABOLISM, INBORN ERRORS).
Terms: Histidine Ammonia-Lyase Preferred Term
Term UI T019995
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1973); Histidinase
Term UI T019998
Date03/11/1994
LexicalTag NON
ThesaurusID NLM (1995); Histidine Deaminase
Term UI T019997
Date03/11/1994
LexicalTag NON
ThesaurusID NLM (1995); Histidase
Term UI T019994
Date11/15/1996
LexicalTag NON
ThesaurusID NLM (1998); Histidine alpha-Deaminase
Term UI T019996
Date03/11/1994
LexicalTag NON
ThesaurusID NLM (1995)

Histidine Ammonia-Lyase MeSH Descriptor Data 2024