MeSH Browser

MeSH Heading: Hydrochlorothiazide
Tree Number(s): D02.886.590.700.135.261.476; D02.886.655.500.261.476; D03.633.100.174.261.476
Unique ID: D006852
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006852
Scope Note: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
Entry Term(s): Dichlothiazide; Dihydrochlorothiazide; Esidrex; Esidrix; HCTZ; HydroDIURIL; Hypothiazide; Oretic; Sectrazide
Pharm Action: Antihypertensive Agents
Diuretics
Sodium Chloride Symporter Inhibitors
Related Numbers: 58-93-5
CAS Type 1 Name: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide
NLM Classification #: QV 160
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0010703
Related Numbers: 58-93-5
Scope Note: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
Terms: Hydrochlorothiazide Preferred Term
Term UI T020666
Date01/01/1999
LexicalTag NON
ThesaurusID; Dichlothiazide
Term UI T020662
Date01/03/1985
LexicalTag NON
ThesaurusID UNK (19XX); Dihydrochlorothiazide
Term UI T020663
Date01/08/1981
LexicalTag NON
ThesaurusID UNK (19XX); HCTZ
Term UI T020665
Date10/29/1986
LexicalTag ABB
ThesaurusID

Hydrochlorothiazide MeSH Descriptor Data 2024