MeSH Browser

MeSH Heading: Large Neutral Amino Acid-Transporter 1
Tree Number(s): D12.776.157.530.200.500.500.500.300.500; D12.776.157.530.937.313.500.625.500; D12.776.543.585.200.500.500.500.500.500; D12.776.543.585.937.313.500.625.500
Unique ID: D027283
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D027283
Scope Note: A CD98 antigen light chain that when heterodimerized with CD98 antigen heavy chain (FUSION REGULATORY PROTEIN-1 HEAVY CHAIN) forms a protein that mediates sodium-independent L-type amino acid transport.
Entry Term(s): E16 Membrane Protein; LAT1 Protein; Membrane Protein E16; SLC7A5; SLC7A5 Protein; Solute Carrier Family-7 (Cationic Amino Acid Transporter, y+ System), Member 5
Registry Numbers: 0
Previous Indexing: Carrier Proteins (1999-2001); Membrane Proteins (1995-2001)
Public MeSH Note: 2002; for MEMBRANE PROTEIN E16 see LARGE NEUTRAL AMINO ACID-TRANSPORTER 1 1995-2001; for LAT1 PROTEIN see AMINO ACID TRANSPORT SYSTEMS 1999-2001; for SLC7A5 see BASIC AMINO ACID TRANSPORT SYSTEMS 1999-2001; MEMBRANE PROTEIN E16 was indexed under MEMBRANE PROTEINS 1995-2001; LAT1 PROTEIN was indexed under CARRIER PROTEINS 1999-2001; SCL7A5 was indexed under CARRIER PROTEINS & MEMBRANE PROTEINS 1999-2001
History Note: 2002; for MEMBRANE PROTEIN E16 use LARGE NEUTRAL AMINO ACID-TRANSPORTER 1 1995-2001; for LAT1 PROTEIN use AMINO ACID TRANSPORT SYSTEMS 1999-2001; for SLC7A5 use BASIC AMINO ACID TRANSPORT SYSTEMS 1999-2001
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2017/07/13

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Amino Acid Transport Systems [D12.776.157.530.200]
        
        Amino Acid Transport Systems, Neutral [D12.776.157.530.200.500]
        
        Amino Acid Transport System L [D12.776.157.530.200.500.500]
        
        Fusion Regulatory Protein-1 [D12.776.157.530.200.500.500.500]
        
        Fusion Regulatory Protein 1, Light Chains [D12.776.157.530.200.500.500.500.300]
        
        Large Neutral Amino Acid-Transporter 1 [D12.776.157.530.200.500.500.500.300.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Solute Carrier Proteins [D12.776.157.530.937]
        
        Amino Acid Transport System y+L [D12.776.157.530.937.313]
        
        Fusion Regulatory Protein-1 [D12.776.157.530.937.313.500]
        
        Fusion Regulatory Protein 1, Light Chains [D12.776.157.530.937.313.500.625]
        
        Large Neutral Amino Acid-Transporter 1 [D12.776.157.530.937.313.500.625.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Amino Acid Transport Systems [D12.776.543.585.200]
        
        Amino Acid Transport Systems, Neutral [D12.776.543.585.200.500]
        
        Amino Acid Transport System L [D12.776.543.585.200.500.500]
        
        Fusion Regulatory Protein-1 [D12.776.543.585.200.500.500.500]
        
        Fusion Regulatory Protein 1, Light Chains [D12.776.543.585.200.500.500.500.500]
        
        Large Neutral Amino Acid-Transporter 1 [D12.776.543.585.200.500.500.500.500.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Solute Carrier Proteins [D12.776.543.585.937]
        
        Amino Acid Transport System y+L [D12.776.543.585.937.313]
        
        Fusion Regulatory Protein-1 [D12.776.543.585.937.313.500]
        
        Fusion Regulatory Protein 1, Light Chains [D12.776.543.585.937.313.500.625]
        
        Large Neutral Amino Acid-Transporter 1 [D12.776.543.585.937.313.500.625.500]

Large Neutral Amino Acid-Transporter 1 Preferred

Concept UI: M0151515
Registry Numbers: 0
Scope Note: A CD98 antigen light chain that when heterodimerized with CD98 antigen heavy chain (FUSION REGULATORY PROTEIN-1 HEAVY CHAIN) forms a protein that mediates sodium-independent L-type amino acid transport.
Terms: Large Neutral Amino Acid-Transporter 1 Preferred Term
Term UI T437295
Date02/27/2001
LexicalTag NON
ThesaurusID NLM (2002); E16 Membrane Protein
Term UI T271741
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2002); Membrane Protein E16
Term UI T271743
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2002); SLC7A5
Term UI T230002
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2002); SLC7A5 Protein
Term UI T437299
Date02/27/2001
LexicalTag ACX
ThesaurusID NLM (2002); Solute Carrier Family-7 (Cationic Amino Acid Transporter, y+ System), Member 5
Term UI T437300
Date02/27/2001
LexicalTag NON
ThesaurusID NLM (2002); LAT1 Protein
Term UI T181520
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2002)

Large Neutral Amino Acid-Transporter 1 MeSH Descriptor Data 2025