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N-Acetylgalactosamine-4-Sulfatase MeSH Descriptor Data 2025
An arylsulfatase that catalyzes the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate. A deficiency of this enzyme is responsible for the inherited lysosomal disease, Maroteaux-Lamy syndrome (MUCOPOLYSACCHARIDOSIS VI). EC 3.1.6.12.
1999; for ARYLSULFATASE B see CHONDRO-4-SULFATASE 1975-1998; N-ACETYLGALACTOSAMINE-4-SULFATE SULFATASE (now N-ACETYLGALACTOSAMINE-4-SULFATASE) was indexed under SULFATASES 1988-1998
History Note
1999; for ARYLSULFATASE B use CHONDRO-4-SULFATASE 1975-1998; use N-ACETYLGALACTOSAMINE-4-SULFATASE (NM) 1988-1998
An arylsulfatase that catalyzes the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate. A deficiency of this enzyme is responsible for the inherited lysosomal disease, Maroteaux-Lamy syndrome (MUCOPOLYSACCHARIDOSIS VI). EC 3.1.6.12.