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Naltrexone MeSH Descriptor Data 2023


MeSH Heading
Naltrexone
Tree Number(s)
D03.132.577.249.706.550
D03.605.497.750.550
D03.633.400.686.750.550
D04.615.723.795.706.550
Unique ID
D009271
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D009271
Scope Note
Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of NALOXONE. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Entry Term(s)
Antaxone
Celupan
EN-1639A
Nalorex
Naltrexone Hydrochloride
Nemexin
ReVia
Trexan
Pharm Action
Alcohol Deterrents
Narcotic Antagonists
Registry Number
5S6W795CQM
Related Numbers
16590-41-3
Z6375YW9SF
CAS Type 1 Name
Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5alpha)-
NLM Classification #
QV 89
Previous Indexing
Cyclopropanes (1973-1975)
Morphinans (1973-1974)
Naloxone/analogs & derivatives (1975)
Public MeSH Note
1986; NALTREXONE was indexed under NALOXONE 1976-1985
History Note
1986 (1976)
Date Established
1986/01/01
Date of Entry
1975/07/23
Revision Date
2018/04/10
Naltrexone Preferred
Antaxone Narrower
Trexan Narrower
EN-1639A Narrower
ReVia Narrower
Naltrexone Hydrochloride Narrower
Celupan Narrower
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