MeSH Browser

MeSH Heading: Neuromuscular Depolarizing Agents
Tree Number(s): D27.505.696.663.700.710.550
Unique ID: D009467
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009467
Scope Note: Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation.
Entry Term(s): Depolarizing Blockers; Depolarizing Muscle Relaxants; Muscle Relaxants, Depolarizing
NLM Classification #: QV 140
Previous Indexing: Muscles (1966-1969)
Public MeSH Note: 70; LEPTOCURARES was see NEUROMUSCULAR DEPOLARIZING AGENTS 1970-92; MUSCLE RELAXANTS was see under CURARE-LIKE AGENTS & MUSCLE RELAXANTS, CENTRAL & NEUROMUSCULAR DEPOLARIZING AGENTS 1970-74, was heading 1963-69
Online Note: use NEUROMUSCULAR DEPOLARIZING AGENTS to search LEPTOCURARES 1970-92; search MUSCLE RELAXANTS under CURARE-LIKE AGENTS & MUSCLE RELAXANTS, CENTRAL & NEUROMUSCULAR DEPOLARIZING AGENTS 1970-74 & MUSCLES 1966-69
History Note: 70; LEPTOCURARES was see NEUROMUSCULAR DEPOLARIZING AGENTS 1970-92; MUSCLE RELAXANTS was see under CURARE-LIKE AGENTS & MUSCLE RELAXANTS, CENTRAL & NEUROMUSCULAR DEPOLARIZING AGENTS 1970-74, was heading 1963-69
Date Established: 1970/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0014724
Scope Note: Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation.
Terms: Neuromuscular Depolarizing Agents Preferred Term
Term UI T028212
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1970); Depolarizing Muscle Relaxants
Term UI T028210
Date03/30/1974
LexicalTag NON
ThesaurusID UNK (19XX); Muscle Relaxants, Depolarizing
Term UI T028211
Date04/10/1978
LexicalTag NON
ThesaurusID UNK (19XX); Depolarizing Blockers
Term UI T028213
Date02/14/1994
LexicalTag NON
ThesaurusID NLM (1995)

Neuromuscular Depolarizing Agents MeSH Descriptor Data 2024