MeSH Browser

MeSH Heading: Nucleoside-Diphosphate Kinase
Tree Number(s): D08.811.913.696.650.550
Unique ID: D009701
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009701
Scope Note: An enzyme that is found in mitochondria and in the soluble cytoplasm of cells. It catalyzes reversible reactions of a nucleoside triphosphate, e.g., ATP, with a nucleoside diphosphate, e.g., UDP, to form ADP and UTP. Many nucleoside diphosphates can act as acceptor, while many ribo- and deoxyribonucleoside triphosphates can act as donor. EC 2.7.4.6.
Entry Term(s): Deoxynucleoside Diphosphate Kinases; GDP Kinase; Nucleoside Diphosphokinases; Nucleoside-Diphosphate Kinases
Registry Numbers: EC 2.7.4.6; 0
Related Numbers: 9026-51-1
CAS Type 1 Name: ATP:nucleoside-diphosphate phosphotransferase
Previous Indexing: Nucleotides (1966-1976); Phosphotransferases (1966-1973); Phosphotransferases, ATP (1974-1976)
Public MeSH Note: 94; was NUCLEOSIDE DIPHOSPHATE KINASES 1977-93 (see under PHOSPHOTRANSFERASES, ATP 1977-90)
Online Note: use NUCLEOSIDE-DIPHOSPHATE KINASE to search NUCLEOSIDE DIPHOSPHATE KINASES 1977-93
History Note: 94; was NUCLEOSIDE DIPHOSPHATE KINASES 1977-93 (see under PHOSPHOTRANSFERASES, ATP 1977-90)
Date Established: 1991/01/01
Date of Entry: 1976/05/19
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0015062
Registry Numbers: EC 2.7.4.6
Related Numbers: 9026-51-1
Scope Note: An enzyme that is found in mitochondria and in the soluble cytoplasm of cells. It catalyzes reversible reactions of a nucleoside triphosphate, e.g., ATP, with a nucleoside diphosphate, e.g., UDP, to form ADP and UTP. Many nucleoside diphosphates can act as acceptor, while many ribo- and deoxyribonucleoside triphosphates can act as donor. EC 2.7.4.6.
Terms: Nucleoside-Diphosphate Kinase Preferred Term
Term UI T028837
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1977); Deoxynucleoside Diphosphate Kinases
Term UI T028835
Date12/16/1985
LexicalTag NON
ThesaurusID UNK (19XX); Nucleoside-Diphosphate Kinases
Term UI T028836
Date06/18/1993
LexicalTag NON
ThesaurusID NLM (1994); Nucleoside Diphosphokinases
Term UI T028838
Date06/25/1981
LexicalTag NON
ThesaurusID UNK (19XX)

Nucleoside-Diphosphate Kinase MeSH Descriptor Data 2024