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Paclitaxel MeSH Descriptor Data 2023


MeSH Heading
Paclitaxel
Tree Number(s)
D02.455.426.392.368.242.888.777
D02.455.849.291.850.777
Unique ID
D017239
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017239
Scope Note
A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.
Entry Term(s)
7-epi-Taxol
Anzatax
Bris Taxol
NSC-125973
Onxol
Paclitaxel, (4 alpha)-Isomer
Paxene
Praxel
Taxol
Taxol A
Pharm Action
Antineoplastic Agents, Phytogenic
Tubulin Modulators
Registry Number
P88XT4IS4D
Related Numbers
105454-04-4
33069-62-4
CAS Type 1 Name
Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,1-2alpha,12aalpha,12balpha))-
NLM Classification #
QV 269
Previous Indexing
Alkaloids (1982-1992)
Terpenes (1977-1981)
Public MeSH Note
95; was TAXOL 1993-94; TAXOL A was indexed under ALKALOIDS 1982-92 & TERPENES 1977-81
Online Note
use PACLITAXEL to search TAXOL 1993-94; use PACLITAXEL (NM) to search TAXOL A 1977-92
History Note
95; was TAXOL 1993-94; was TAXOL A (NM) 1977-92
Date Established
1993/01/01
Date of Entry
1999/11/04
Revision Date
2014/10/14
Paclitaxel Preferred
Anzatax Narrower
NSC-125973 Narrower
Taxol Narrower
Paclitaxel, (4 alpha)-Isomer Narrower
Paxene Narrower
Praxel Narrower
7-epi-Taxol Related
Onxol Narrower
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