Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

poly(A)-specific ribonuclease MeSH Supplementary Concept Data 2025


MeSH Supplementary
poly(A)-specific ribonuclease
Unique ID
C062401
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C062401
Entry Term(s)
AHG2 protein, Arabidopsis
PAN2 protein, S cerevisiae
PARN protein, Arabidopsis
PARN protein, human
PARN1 protein, C elegans
YGL094C protein, S cerevisiae
deadenylation nuclease, human
mRNA poly(A) nuclease
parn-A protein, Xenopus
poly(A) nuclease
poly(A) ribonuclease (PAN)
poly(A) ribonuclease , Arabidopsis
poly(A)-specific ribonuclease, Xenopus
poly(A)-specific ribonuclease, human
poly(A)ribonuclease
xPARN protein, Xenopus
Registry Numbers
EC 3.1.13.4
Heading Mapped to
*Exoribonucleases
Frequency
173
Note
bifunctional enzyme responsible for both poly(A)-polymerizing & poly(A)-hydrolyzing activities; removes the poly(A) tail as the first step in degrading mRNA; RefSeq NM_002582 (human)
Source
Eur J Biochem 1989;186(3):591
Indexing Information
Arabidopsis Proteins
Saccharomyces cerevisiae Proteins
Xenopus Proteins
Date of Entry
1990/02/15
Revision Date
2024/01/26
poly(A)-specific ribonuclease Preferred
PAN2 protein, S cerevisiae Narrower
PARN protein, human Narrower
parn-A protein, Xenopus Narrower
PARN protein, Arabidopsis Narrower
page delivered in 0.004s