MeSH Browser

MeSH Heading: Exoribonucleases
Tree Number(s): D08.811.277.352.365.300; D08.811.277.352.700.375
Unique ID: D005095
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D005095
Scope Note: A family of enzymes that catalyze the exonucleolytic cleavage of RNA. It includes EC 3.1.13.-, EC 3.1.14.-, EC 3.1.15.-, and EC 3.1.16.-. EC 3.1.-
Entry Term(s): Exoribonuclease; Poly(A) Nuclease; Poly(A) Ribonuclease (PAN); Poly(A)-Specific Ribonuclease; Poly(A)ribonuclease; mRNA Poly(A) Nuclease
Registry Numbers: EC 3.1.-; EC 3.1.13.4
Previous Indexing: Exonucleases (1973-1982); Phosphatases (1966-1972); Ribonucleases (1966-1982)
Public MeSH Note: 2026; POLY(A)-SPECIFIC RIBONUCLEASE (NM) was indexed under EXORIBONUCLEASES 1990-2025
History Note: 2026(1983)
Date Introduced: 1983/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0172742
Registry Numbers: EC 3.1.13.4
Scope Note: 3'-exoribonuclease that degrades poly(A) tails of mRNAs.
Terms: Poly(A)-Specific Ribonuclease Preferred Term
Term UI T001148967
Date06/11/2025
LexicalTag ABX
ThesaurusID NLM (1990); mRNA Poly(A) Nuclease
Term UI T001148968
Date06/11/2025
LexicalTag ABX
ThesaurusID NLM (1990); Poly(A) Nuclease
Term UI T001148969
Date06/11/2025
LexicalTag ABX
ThesaurusID NLM (1990); Poly(A) Ribonuclease (PAN)
Term UI T001148970
Date06/11/2025
LexicalTag ABX
ThesaurusID NLM (1990); Poly(A)ribonuclease
Term UI T001148971
Date06/11/2025
LexicalTag ABX
ThesaurusID NLM (2001)

Exoribonucleases MeSH Descriptor Data 2026