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Receptors, Polymeric Immunoglobulin MeSH Descriptor Data 2022


MeSH Heading
Receptors, Polymeric Immunoglobulin
Tree Number(s)
D12.776.543.750.705.871.700
Unique ID
D019056
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019056
Scope Note
Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)
Entry Version
RECEPT POLY IG
Entry Term(s)
Poly-Ig Receptor
Polyimmunoglobulin Receptor
Polymeric Ig Receptor
Polymeric Immunoglobulin Receptor
Polymeric Immunoglobulin Receptors
Receptor, Polyimmunoglobulin
Receptor, Polymeric Ig
Registry Number
0
Previous Indexing
Receptors, Immunologic (1989-1995)
Secretory Component (1992-1995)
Public MeSH Note
96
History Note
96
Date Established
1996/01/01
Date of Entry
1995/05/26
Revision Date
2018/07/01
Receptors, Polymeric Immunoglobulin Preferred
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