MeSH Browser

MeSH Heading: Receptors, Polymeric Immunoglobulin
Tree Number(s): D12.776.543.750.705.871.700
Unique ID: D019056
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019056
Scope Note: Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)
Entry Version: RECEPT POLY IG
Entry Term(s): Poly-Ig Receptor; Polyimmunoglobulin Receptor; Polymeric Ig Receptor; Polymeric Immunoglobulin Receptor; Polymeric Immunoglobulin Receptors; Receptor, Polyimmunoglobulin; Receptor, Polymeric Ig
Previous Indexing: Receptors, Immunologic (1989-1995); Secretory Component (1992-1995)
Public MeSH Note: 96
History Note: 96
Date Established: 1996/01/01
Date of Entry: 1995/05/26
Revision Date: 2018/07/01

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Receptors, Fc [D12.776.543.750.705.871]
        
        Receptors, IgE [D12.776.543.750.705.871.280]
        
        Receptors, IgG [D12.776.543.750.705.871.300]
        
        Receptors, Polymeric Immunoglobulin [D12.776.543.750.705.871.700]

Receptors, Polymeric Immunoglobulin Preferred

Concept UI: M0028447
Scope Note: Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)
Terms: Receptors, Polymeric Immunoglobulin Preferred Term
Term UI T056910
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1996); Polymeric Immunoglobulin Receptor
Term UI T056908
Date03/21/1995
LexicalTag NON
ThesaurusID NLM (1996); Polymeric Immunoglobulin Receptors
Term UI T056909
Date03/21/1995
LexicalTag NON
ThesaurusID NLM (1996); Polymeric Ig Receptor
Term UI T056911
Date02/02/1995
LexicalTag NON
ThesaurusID NLM (1996); Receptor, Polymeric Ig
Term UI T056912
Date03/21/1995
LexicalTag NON
ThesaurusID NLM (1996); Poly-Ig Receptor
Term UI T056913
Date03/13/1995
LexicalTag NON
ThesaurusID NLM (1996); Polyimmunoglobulin Receptor
Term UI T056914
Date02/02/1995
LexicalTag NON
ThesaurusID NLM (1996); Receptor, Polyimmunoglobulin
Term UI T056915
Date03/21/1995
LexicalTag NON
ThesaurusID NLM (1996)

Receptors, Polymeric Immunoglobulin MeSH Descriptor Data 2024