MeSH Browser

MeSH Heading: Amyloid Precursor Protein Secretases
Tree Number(s): D08.811.277.656.300.032
Unique ID: D053829
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053829
Scope Note: Endopeptidases that are specific for AMYLOID PROTEIN PRECURSOR. Three secretase subtypes referred to as alpha, beta, and gamma have been identified based upon the region of amyloid protein precursor they cleave.
Entry Term(s): APP Secretase; Amyloid Precursor Protein Secretase; Secretase; Secretases; alpha-Secretase; beta-Secretase; gamma-Secretase
Registry Numbers: EC 3.4.-; EC 3.4.-; EC 3.4.-; EC 3.4.-
Related Numbers: EC 3.4.-
Public MeSH Note: 2007; SECRETASE was indexed under ENDOPEPTIDASES 1992-2006
History Note: 2007(1992)
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0205216
Registry Numbers: EC 3.4.-
Related Numbers: EC 3.4.-
Scope Note: Endopeptidases that are specific for AMYLOID PROTEIN PRECURSOR. Three secretase subtypes referred to as alpha, beta, and gamma have been identified based upon the region of amyloid protein precursor they cleave.
Terms: Amyloid Precursor Protein Secretases Preferred Term
Term UI T670714
Date04/05/2006
LexicalTag NON
ThesaurusID NLM (2007); Amyloid Precursor Protein Secretase
Term UI T418307
Date07/06/2000
LexicalTag NON
ThesaurusID NLM (2007); APP Secretase
Term UI T418308
Date07/06/2000
LexicalTag ABX
ThesaurusID NLM (2007); Secretase
Term UI T235221
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Secretases
Term UI T670715
Date04/05/2006
LexicalTag NON
ThesaurusID NLM (2007)

Amyloid Precursor Protein Secretases MeSH Descriptor Data 2025