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Secretory Component MeSH Descriptor Data 2025


MeSH Heading
Secretory Component
Tree Number(s)
D12.776.124.486.485.114.619.026.030.500
D12.776.124.486.485.705.875
D12.776.124.790.651.114.619.026.030.500
D12.776.124.790.651.705.875
D12.776.377.715.548.114.619.026.030.500
D12.776.377.715.548.705.875
Unique ID
D012635
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D012635
Scope Note
The extracellular moiety of the POLYMERIC IMMUNOGLOBULIN RECEPTOR found alone or complexed with IGA or IGM, in a variety of external secretions (tears, bile, colostrum.) Secretory component is derived by proteolytic cleavage of the receptor during transcytosis. When immunoglobulins IgA and IgM are bound to the receptor, during their transcytosis secretory component becomes covalently attached to them generating SECRETORY IMMUNOGLOBULIN A or secretory IMMUNOGLOBULIN M.
Entry Version
SECRET COMPONENT
Entry Term(s)
Secretory Piece
Pharm Action
Immunologic Factors
Registry Numbers
0
Previous Indexing
Colostrum (1973-1975)
IgA (1973-1975)
Immunoglobulin Fragments (1973-1975)
Public MeSH Note
91; was see under IMMUNOGLOBULIN FRAGMENTS 1976-90
History Note
91(76); was see under IMMUNOGLOBULIN FRAGMENTS 1976-90
Date Established
1991/01/01
Date of Entry
1975/07/25
Revision Date
2005/06/30
Secretory Component Preferred
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