MeSH Browser

MeSH Heading: Monomeric GTP-Binding Proteins
Tree Number(s): D08.811.277.040.330.300.400; D12.776.157.325.515; D12.776.476.338.400
Unique ID: D020559
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020559
Scope Note: A class of monomeric, low molecular weight (20-25 kDa) GTP-binding proteins that regulate a variety of intracellular processes. The GTP bound form of the protein is active and limited by its inherent GTPase activity, which is controlled by an array of GTPase activators, GDP dissociation inhibitors, and guanine nucleotide exchange factors. This enzyme was formerly listed as EC 3.6.1.47
Entry Term(s): G-Proteins, Monomeric; GTP-Binding Proteins, Monomeric; Monomeric G-Protein; Monomeric G-Proteins; Small G-Protein; Small G-Proteins; Small GTPase; Small GTPases; ras-Related G-Proteins; ras-Related GTP-Binding Protein; ras-Related GTP-Binding Proteins; ras-Related GTPase; ras-Related GTPases
Registry Numbers: EC 3.6.5.2; EC 3.6.1.-
Previous Indexing: GTP-Binding Proteins (1997-1999); Heterotrimeric GTP-Binding Proteins (1985-1996)
Public MeSH Note: 2000
History Note: 2000
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2021/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0328207
Registry Numbers: EC 3.6.5.2
Scope Note: A class of monomeric, low molecular weight (20-25 kDa) GTP-binding proteins that regulate a variety of intracellular processes. The GTP bound form of the protein is active and limited by its inherent GTPase activity, which is controlled by an array of GTPase activators, GDP dissociation inhibitors, and guanine nucleotide exchange factors. This enzyme was formerly listed as EC 3.6.1.47
Terms: Monomeric GTP-Binding Proteins Preferred Term
Term UI T358207
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Small GTPase
Term UI T000996364
Date11/14/2019
LexicalTag NON
ThesaurusID NLM (2021); G-Proteins, Monomeric
Term UI T358926
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); GTP-Binding Proteins, Monomeric
Term UI T358927
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Monomeric G-Proteins
Term UI T358928
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Small G-Proteins
Term UI T358929
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Small GTPases
Term UI T358930
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Monomeric G-Protein
Term UI T001089434
Date10/06/2020
LexicalTag NON
ThesaurusID NLM (2022); Small G-Protein
Term UI T001089435
Date10/06/2020
LexicalTag NON
ThesaurusID NLM (2022)

Concept UI: M0328880
Registry Numbers: EC 3.6.1.-
Terms: ras-Related GTPases Preferred Term
Term UI T358924
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); ras-Related G-Proteins
Term UI T358931
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); ras-Related GTP-Binding Proteins
Term UI T358932
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); ras-Related GTPase
Term UI T001089436
Date10/06/2020
LexicalTag NON
ThesaurusID NLM (2022); ras-Related GTP-Binding Protein
Term UI T001089437
Date10/06/2020
LexicalTag NON
ThesaurusID NLM (2022)

Monomeric GTP-Binding Proteins MeSH Descriptor Data 2025