MeSH Browser

MeSH Heading: RNA, Small Nucleolar
Tree Number(s): D13.444.735.628.818.800; D13.444.735.790.552.937.800
Unique ID: D020537
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020537
Scope Note: Small nuclear RNAs that are involved in the processing of pre-ribosomal RNA in the nucleolus. Box C/D containing snoRNAs (U14, U15, U16, U20, U21 and U24-U63) direct site-specific methylation of various ribose moieties. Box H/ACA containing snoRNAs (E2, E3, U19, U23, and U64-U72) direct the conversion of specific uridines to pseudouridine. Site-specific cleavages resulting in the mature ribosomal RNAs are directed by snoRNAs U3, U8, U14, U22 and the snoRNA components of RNase MRP and RNase P.
Entry Term(s): Small Nucleolar RNA; snoRNA
Registry Numbers: 0
Previous Indexing: Cell Nucleolus (1975-1999); RNA (1975-1985); RNA, Small Nuclear (1986-1999)
Public MeSH Note: 2000
History Note: 2000
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2010/06/25

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0328073
Registry Numbers: 0
Scope Note: Small nuclear RNAs that are involved in the processing of pre-ribosomal RNA in the nucleolus. Box C/D containing snoRNAs (U14, U15, U16, U20, U21 and U24-U63) direct site-specific methylation of various ribose moieties. Box H/ACA containing snoRNAs (E2, E3, U19, U23, and U64-U72) direct the conversion of specific uridines to pseudouridine. Site-specific cleavages resulting in the mature ribosomal RNAs are directed by snoRNAs U3, U8, U14, U22 and the snoRNA components of RNase MRP and RNase P.
Terms: RNA, Small Nucleolar Preferred Term
Term UI T358073
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); snoRNA
Term UI T361769
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Small Nucleolar RNA
Term UI T361770
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000)

RNA, Small Nucleolar MeSH Descriptor Data 2024