NLM Logo

Sp1 Transcription Factor MeSH Descriptor Data 2024


MeSH Heading
Sp1 Transcription Factor
Tree Number(s)
D12.776.260.522.750.249
D12.776.930.375.750.249
Unique ID
D016329
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016329
Annotation
/drug eff /‌ultrastruct permitted; in titles & translations use SP1 (the figure one), not SPl (the letter l)
Scope Note
Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.
Entry Term(s)
Specificity Protein 1 Transcription Factor
Transcription Factor, Sp1
Previous Indexing
DNA-Binding Proteins (1986-1990)
Transcription Factors (1986-1990)
Public MeSH Note
2006; see TRANSCRIPTION FACTOR, SP1 1991-2005
History Note
2006(1991)
Date Established
1991/01/01
Date of Entry
1990/06/19
Revision Date
2009/07/14
Sp1 Transcription Factor Preferred
page delivered in 0.148s