MeSH Browser

MeSH Heading: Toll-Like Receptors
Tree Number(s): D12.776.543.750.705.910.500
Unique ID: D051193
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051193
Annotation: general; prefer specifics
Scope Note: A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
Entry Term(s): Receptors, Toll-Like; Toll-Like Receptor
Registry Numbers: 0
NLM Classification #: QW 569
Public MeSH Note: 2006; TOLL-LIKE RECEPTOR was indexed under MEMBRANE GLYCOPROTEINS & RECEPTORS, CELL SURFACE 1998-2005
History Note: 2006(1998)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Concept UI: M0286281
Registry Numbers: 0
Scope Note: A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
Terms: Toll-Like Receptors Preferred Term
Term UI T316280
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Receptors, Toll-Like
Term UI T628374
Date01/20/2005
LexicalTag NON
ThesaurusID NLM (2006); Toll-Like Receptor
Term UI T316286
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006)

Toll-Like Receptors MeSH Descriptor Data 2024