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Loperamide MeSH Descriptor Data 2022


MeSH Heading
Loperamide
Tree Number(s)
D03.383.621.440
Unique ID
D008139
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D008139
Scope Note
One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
Entry Term(s)
Imodium
Loperamide Hydrochloride
Loperamide Monohydrochloride
R-18553
Pharm Action
Antidiarrheals
Registry Number
6X9OC3H4II
Related Numbers
34552-83-5
53179-11-6
77TI35393C
CAS Type 1 Name
1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-
NLM Classification #
QV 71
Previous Indexing
Amides (1974-1975)
Chlorobenzenes (1974-1975)
Piperidines (1974-1975)
Public MeSH Note
91; was see under PIPERIDINES 1976-90
History Note
91(76); was see under PIPERIDINES 1976-90
Date Established
1991/01/01
Date of Entry
1975/07/23
Revision Date
2016/05/31
Loperamide Preferred
R-18553 Narrower
Imodium Narrower
Loperamide Hydrochloride Narrower
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