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N-((2S,3S)-4,4-difluoro-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl)-4-((4-(morpholinomethyl)phenyl)ethynyl)benzamide
MeSH Supplementary Concept Data 2025
Details
Concepts
MeSH Supplementary
N-((2S,3S)-4,4-difluoro-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl)-4-((4-(morpholinomethyl)phenyl)ethynyl)benzamide
Unique ID
C000626788
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C000626788
Entry Term(s)
LPC-069
Pharm Action
Anti-Bacterial Agents
Enzyme Inhibitors
Registry Numbers
0
Heading Mapped to
*Benzamides
*Morpholines
Frequency
1
Note
inhibitor of LpxC, an essential enzyme in the biosynthesis of the lipid A component of the outer membrane of Gram-negative bacteria
Source
MBio. 2017 Jul 25;8(4). pii: e00674-17.
Date of Entry
2018/04/18
Revision Date
2018/04/18
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N-((2S,3S)-4,4-difluoro-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl)-4-((4-(morpholinomethyl)phenyl)ethynyl)benzamide
Preferred
Concept UI
M000642464
Registry Numbers
0
Terms
N-((2S,3S)-4,4-difluoro-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl)-4-((4-(morpholinomethyl)phenyl)ethynyl)benzamide
Preferred Term
Term UI
T000942211
Date
04/18/2018
LexicalTag
NON
ThesaurusID
NLM (2017)
LPC-069
Narrower
Concept UI
M000642465
Registry Numbers
0
Terms
LPC-069
Preferred Term
Term UI
T000942212
Date
04/18/2018
LexicalTag
LAB
ThesaurusID
NLM (2017)
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