Toggle navigation
Search
Tree View
MeSH on Demand
MeSH 2025
About
Suggestions
Contact Us
Enzyme Inhibitors
MeSH Descriptor Data 2024
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Enzyme Inhibitors
Tree Number(s)
D27.505.519.389
Unique ID
D004791
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004791
Annotation
general or unspecified; prefer specifics
Scope Note
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Entry Version
ENZYME INHIB
Entry Term(s)
Enzyme Inhibitor
NLM Classification #
QU 143
Previous Indexing
Enzymes (1966-1967)
Enzymes/antagonists & inhibitors (1968-1974)
Public MeSH Note
1975, 1964-1967
History Note
1975(1964)
Date Established
1975/09/01
Date of Entry
1999/01/01
Revision Date
2021/03/04
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
analysis (AN)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
economics (EC)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
urine (UR)
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Alkylating Agents [D27.505.519.124]
Amylin Receptor Agonists [D27.505.519.143]
Angiotensin Receptor Antagonists [D27.505.519.162]
Antacids [D27.505.519.170]
Antidiuretic Hormone Receptor Antagonists [D27.505.519.174]
Antifoaming Agents [D27.505.519.178]
Antiglycation Agents [D27.505.519.182]
Antimetabolites [D27.505.519.186]
Antioxidants [D27.505.519.217]
Aversive Agents [D27.505.519.241]
Bradykinin Receptor Antagonists [D27.505.519.265]
Calcitonin Gene-Related Peptide Receptor Antagonists [D27.505.519.270]
CCR5 Receptor Antagonists [D27.505.519.275]
Cerumenolytic Agents [D27.505.519.295]
Cystine Depleting Agents [D27.505.519.334]
Cytochrome P-450 Enzyme Inducers [D27.505.519.349]
Endothelin Receptor Antagonists [D27.505.519.364]
Enzyme Activators [D27.505.519.374]
Enzyme Inhibitors [D27.505.519.389]
5-Lipoxygenase-Activating Protein Inhibitors [D27.505.519.389.086]
Acetaldehyde Dehydrogenase Inhibitors [D27.505.519.389.089]
Adenosine Deaminase Inhibitors [D27.505.519.389.092]
Adenylyl Cyclase Inhibitors [D27.505.519.389.108]
Aromatic Amino Acid Decarboxylase Inhibitors [D27.505.519.389.124]
Calcineurin Inhibitors [D27.505.519.389.174]
Carbonic Anhydrase Inhibitors [D27.505.519.389.200]
Catechol O-Methyltransferase Inhibitors [D27.505.519.389.237]
Cholinesterase Inhibitors [D27.505.519.389.275]
Cyclooxygenase Inhibitors [D27.505.519.389.310]
Gamma Secretase Inhibitors and Modulators [D27.505.519.389.315]
Glycoside Hydrolase Inhibitors [D27.505.519.389.320]
Cytochrome P-450 Enzyme Inhibitors [D27.505.519.389.335]
Folic Acid Antagonists [D27.505.519.389.350]
Histone Deacetylase Inhibitors [D27.505.519.389.360]
Hydroxymethylglutaryl-CoA Reductase Inhibitors [D27.505.519.389.370]
Integrase Inhibitors [D27.505.519.389.375]
beta-Lactamase Inhibitors [D27.505.519.389.400]
Lipoxygenase Inhibitors [D27.505.519.389.480]
Monoamine Oxidase Inhibitors [D27.505.519.389.616]
Nucleic Acid Synthesis Inhibitors [D27.505.519.389.675]
Ornithine Decarboxylase Inhibitors [D27.505.519.389.705]
Phosphodiesterase Inhibitors [D27.505.519.389.735]
Phosphoinositide-3 Kinase Inhibitors [D27.505.519.389.736]
Phospholipase A2 Inhibitors [D27.505.519.389.737]
Poly(ADP-ribose) Polymerase Inhibitors [D27.505.519.389.739]
Prolyl-Hydroxylase Inhibitors [D27.505.519.389.740]
Protease Inhibitors [D27.505.519.389.745]
Protein Kinase Inhibitors [D27.505.519.389.755]
Protein Synthesis Inhibitors [D27.505.519.389.760]
Proton Pump Inhibitors [D27.505.519.389.848]
Steroid Synthesis Inhibitors [D27.505.519.389.870]
Topoisomerase Inhibitors [D27.505.519.389.892]
Uncoupling Agents [D27.505.519.389.936]
Enzyme Reactivators [D27.505.519.405]
Fibrin Modulating Agents [D27.505.519.421]
Heparin Antagonists [D27.505.519.452]
Immune Checkpoint Inhibitors [D27.505.519.507]
Membrane Transport Modulators [D27.505.519.562]
Mitosis Modulators [D27.505.519.593]
Neurotransmitter Agents [D27.505.519.625]
Nitric Oxide Donors [D27.505.519.656]
Peptidomimetics [D27.505.519.828]
Radiopharmaceuticals [D27.505.519.871]
Sequestering Agents [D27.505.519.914]
Sodium-Glucose Transporter 2 Inhibitors [D27.505.519.936]
Sphingosine 1 Phosphate Receptor Modulators [D27.505.519.947]
Toll-Like Receptor Agonists [D27.505.519.952]
Viral Fusion Protein Inhibitors [D27.505.519.957]
Expand All
Collapse All
Enzyme Inhibitors
Preferred
Concept UI
M0007520
Scope Note
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Terms
Enzyme Inhibitors
Preferred Term
Term UI
T014636
Date
01/01/1999
LexicalTag
NON
ThesaurusID
POPLINE (1978)
Enzyme Inhibitor
Term UI
T000996333
Date
11/14/2019
LexicalTag
NON
ThesaurusID
NLM (2021)
page delivered in 0.157s