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Cholinesterase Inhibitors MeSH Descriptor Data 2022


MeSH Heading
Cholinesterase Inhibitors
Tree Number(s)
D27.505.519.389.275
D27.505.519.625.120.300
D27.505.696.577.120.300
Unique ID
D002800
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002800
Scope Note
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Entry Version
CHOLINESTERASE INHIB
Entry Term(s)
Acetylcholinesterase Inhibitor
Acetylcholinesterase Inhibitors
Anti-Cholinesterase
Anti-Cholinesterases
Anticholinesterase
Anticholinesterase Agent
Anticholinesterase Agents
Anticholinesterase Drug
Anticholinesterase Drugs
Anticholinesterases
Cholinesterase Inhibitor
Cholinesterase Inhibitors, Irreversible
Cholinesterase Inhibitors, Reversible
Registry Number
0
NLM Classification #
QV 124
See Also
Insecticides
Public MeSH Note
65; CHOLINESTERASE INHIBITORS, IRREVERSIBLE & CHOLINESTERASE INHIBITORS, REVERSIBLE were see under CHOLINESTERASE INHIBITORS 1975-83; CHOLINESTERASE INHIBITORS, ORGANIC was see PHOSPHORUS POISONS, ORGANIC 1963-64 (PHOSPHORUS POISONS, ORGANIC deleted 1965)
Online Note
use CHOLINESTERASE INHIBITORS to search CHOLINESTERASE INHIBITORS, IRREVERSIBLE & CHOLINESTERASE INHIBITORS, REVERSIBLE 1971-83 (as Prov 1971-74)
History Note
65; CHOLINESTERASE INHIBITORS, IRREVERSIBLE & CHOLINESTERASE INHIBITORS, REVERSIBLE were see under CHOLINESTERASE INHIBITORS 1975-83, were Prov 1971-74; CHOLINESTERASE INHIBITORS, ORGANIC was see PHOSPHORUS POISONS, ORGANIC 1963-64 (PHOSPHORUS POISONS, ORGANIC deleted 1965)
Date Established
1965/01/01
Date of Entry
1999/01/01
Revision Date
2020/05/27
Cholinesterase Inhibitors Preferred
Cholinesterase Inhibitors, Irreversible Narrower
Cholinesterase Inhibitors, Reversible Narrower
Acetylcholinesterase Inhibitors Narrower
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