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Gamma Secretase Inhibitors and Modulators MeSH Descriptor Data 2022


MeSH Heading
Gamma Secretase Inhibitors and Modulators
Tree Number(s)
D27.505.519.389.315
Unique ID
D000091062
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000091062
Scope Note
Agents that suppress GAMMA-SECRETASE by inhibiting or modulating its activities. Targeted enzymatic activities include its involvement in accumulation of toxic AMYLOID BETA-PEPTIDES (e.g., Aβ42) in ALZHEIMER DISEASE and activation of NOTCH RECEPTOR mediated SIGNAL PATHWAYS in certain cancer types.
Entry Term(s)
GS Inhibitors
GS Inhibitors and Modulators
GS Modulators
Gamma Secretase Inhibitors
Gamma Secretase Modulators
Registry Number
0
Previous Indexing
Amyloid Precursor Protein Secretases (1995-2021)
Public MeSH Note
2022
History Note
2022
Date Established
2022/01/01
Date of Entry
2021/07/09
Revision Date
2021/06/30
Gamma Secretase Inhibitors and Modulators Preferred
Gamma Secretase Modulators Narrower
Gamma Secretase Inhibitors Narrower
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