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Folic Acid Antagonists MeSH Descriptor Data 2022


MeSH Heading
Folic Acid Antagonists
Tree Number(s)
D27.505.519.389.350
Unique ID
D005493
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D005493
Scope Note
Inhibitors of the enzyme, dihydrofolate reductase (TETRAHYDROFOLATE DEHYDROGENASE), which converts dihydrofolate (FH2) to tetrahydrofolate (FH4). They are frequently used in cancer chemotherapy. (From AMA, Drug Evaluations Annual, 1994, p2033)
Entry Version
FOLIC ACID ANTAG
Entry Term(s)
Antifolate
Antifolates
Dihydrofolate Reductase Inhibitor
Dihydrofolate Reductase Inhibitors
Folic Acid Antagonist
Folic Acid Metabolism Inhibitors
Registry Number
0
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2021/06/30
Folic Acid Antagonists Preferred
Folic Acid Metabolism Inhibitors Broader
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