- Concept UI
- M0008662
- Registry Numbers
- 0
- Scope Note
- Inhibitors of the enzyme, dihydrofolate reductase (TETRAHYDROFOLATE DEHYDROGENASE), which converts dihydrofolate (FH2) to tetrahydrofolate (FH4). They are frequently used in cancer chemotherapy. (From AMA, Drug Evaluations Annual, 1994, p2033)
- Terms
-
Folic Acid Antagonists
Preferred Term
Term UI
T016718
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1966)
-
Folic Acid Antagonist
Term UI
T001089577
Date10/07/2020
LexicalTag
NON
ThesaurusID
NLM (2022)
-
Antifolate
Term UI
T001089578
Date10/07/2020
LexicalTag
NON
ThesaurusID
NLM (2022)
-
Dihydrofolate Reductase Inhibitor
Term UI
T001089579
Date10/07/2020
LexicalTag
NON
ThesaurusID
NLM (2022)
-
Antifolates
Term UI
T016719
Date12/06/1994
LexicalTag
NON
ThesaurusID
NLM (1996)
-
Dihydrofolate Reductase Inhibitors
Term UI
T848605
Date08/29/2013
LexicalTag
NON
ThesaurusID
NLM (2015)