MeSH Browser

MeSH Supplementary: sapropterin
Unique ID: C003402
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C003402
Entry Term(s): 1-butanone, 1-(2,4,5-trihydroxyphenyl); 2',4',5'-trihydroxybutyrophenone; 2,4,5-trihydroxybutyrophenone; 5,6,7,8-erythro-tetrahydrobiopterin; 5,6,7,8-tetrahydro-L-erythrobiopterin; 5,6,7,8-tetrahydrobiopterin; 5,6,7,8-tetrahydrobiopterin, (S-(R*,S*))-isomer; 5,6,7,8-tetrahydrodictyopterin; 6R-BH4; 6R-L-erythro-5,6,7,8-tetrahydrobiopterin; D-threo-tetrahydrobiopterin; THBP; kuvan; phenylalanine hydroxylase cofactor; sapropterin dihydrochloride; tetrahydro-6-biopterin; tetrahydrobiopterin; trihydroxybutyrophenone
Registry Numbers: EGX657432I; 0; 27070-47-9; RG277LF5B3; KN729W3LR0
Related Numbers: 17528-72-2; 27070-47-9; KN729W3LR0; RG277LF5B3
Previous Indexing: PROPANEDIOLS (72-75); *PTERIDINES (72-75)
Heading Mapped to: Biopterins / analogs & derivatives
Frequency: 2378
Note: RN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases
Source: Anal Biochem 89(1):71;1978; Ann Clin Lab Sci 7(2):178;1977; Arch Dis Child 53(8):674;1978; Arch Dis Child 54(5):329;1979; Biochem J 157(1):105;1976; Biochem J 171:267;1978; Biochim Biophys Acta 1980;611(1):241; Cancer Biochem Biophys 2(2):71;1978; Cancer Biochem Biophys 2(2):79;1978; Cancer Treat Rep 62(12):1999;1978; J Biol Chem 253(5):1598;1978; J Neural Transm 45(1):4;1979; J Neurochem 30:899;1978; J Neurochem 32(1):179;1979; J Neurochem 32(5):1575;1979; J Pediatr 1980;96(5):854; Lancet 1(7971):1236;1976; Lancet 1(8109):215;1979; Lancet 1(8115):556;1979; Lancet 1(8119):782;1979; Lancet 1(8123):982;1979; Lancet 2(8087):484;1978; Lancet 2(8139):410;1979; N Engl J Med 293(16):787;1975; N Engl J Med 301(8):441;1979; Neuropharmacology 1980;19(1):1; Proc Natl Acad Sci USA 73(5):1591;1976; Science 204(4393):624;1979; Z Naturforsch (C) 27(3):263;1972
Indexing Information: Nitric Oxide; Nitric Oxide Synthase
Date of Entry: 1972/01/01
Revision Date: 2018/09/24

sapropterin Preferred

5,6,7,8-tetrahydrodictyopterin Narrower

5,6,7,8-tetrahydrobiopterin, (S-(R*,S*))-isomer Narrower

D-threo-tetrahydrobiopterin Narrower

sapropterin dihydrochloride Narrower

kuvan Narrower

2,4,5-trihydroxybutyrophenone Related

Concept UI: M000622517
Registry Numbers: KN729W3LR0
Terms: 2,4,5-trihydroxybutyrophenone Preferred Term
Term UI T000908956
Date10/06/2016
LexicalTag NON
ThesaurusID; trihydroxybutyrophenone
Term UI T000908955
Date10/06/2016
LexicalTag NON
ThesaurusID NLM (2017); 2',4',5'-trihydroxybutyrophenone
Term UI T000908957
Date10/06/2016
LexicalTag NON
ThesaurusID NLM (2017); 1-butanone, 1-(2,4,5-trihydroxyphenyl)
Term UI T000908958
Date10/06/2016
LexicalTag NON
ThesaurusID NLM (2017); THBP
Term UI T074449
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (1972)

6R-L-erythro-5,6,7,8-tetrahydrobiopterin Narrower

5,6,7,8-tetrahydrobiopterin Broader

5,6,7,8-erythro-tetrahydrobiopterin Narrower

tetrahydro-6-biopterin Narrower

5,6,7,8-tetrahydro-L-erythrobiopterin Narrower

phenylalanine hydroxylase cofactor Related

sapropterin MeSH Supplementary Concept Data 2025