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sapropterin MeSH Supplementary Concept Data 2025


MeSH Supplementary
sapropterin
Unique ID
C003402
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C003402
Entry Term(s)
1-butanone, 1-(2,4,5-trihydroxyphenyl)
2',4',5'-trihydroxybutyrophenone
2,4,5-trihydroxybutyrophenone
5,6,7,8-erythro-tetrahydrobiopterin
5,6,7,8-tetrahydro-L-erythrobiopterin
5,6,7,8-tetrahydrobiopterin
5,6,7,8-tetrahydrobiopterin, (S-(R*,S*))-isomer
5,6,7,8-tetrahydrodictyopterin
6R-BH4
6R-L-erythro-5,6,7,8-tetrahydrobiopterin
D-threo-tetrahydrobiopterin
THBP
kuvan
phenylalanine hydroxylase cofactor
sapropterin dihydrochloride
tetrahydro-6-biopterin
tetrahydrobiopterin
trihydroxybutyrophenone
Registry Numbers
EGX657432I
0
27070-47-9
RG277LF5B3
KN729W3LR0
Related Numbers
17528-72-2
27070-47-9
KN729W3LR0
RG277LF5B3
Previous Indexing
PROPANEDIOLS (72-75)
*PTERIDINES (72-75)
Heading Mapped to
Biopterins / analogs & derivatives
Frequency
2378
Note
RN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases
Source
Anal Biochem 89(1):71;1978
Ann Clin Lab Sci 7(2):178;1977
Arch Dis Child 53(8):674;1978
Arch Dis Child 54(5):329;1979
Biochem J 157(1):105;1976
Biochem J 171:267;1978
Biochim Biophys Acta 1980;611(1):241
Cancer Biochem Biophys 2(2):71;1978
Cancer Biochem Biophys 2(2):79;1978
Cancer Treat Rep 62(12):1999;1978
J Biol Chem 253(5):1598;1978
J Neural Transm 45(1):4;1979
J Neurochem 30:899;1978
J Neurochem 32(1):179;1979
J Neurochem 32(5):1575;1979
J Pediatr 1980;96(5):854
Lancet 1(7971):1236;1976
Lancet 1(8109):215;1979
Lancet 1(8115):556;1979
Lancet 1(8119):782;1979
Lancet 1(8123):982;1979
Lancet 2(8087):484;1978
Lancet 2(8139):410;1979
N Engl J Med 293(16):787;1975
N Engl J Med 301(8):441;1979
Neuropharmacology 1980;19(1):1
Proc Natl Acad Sci USA 73(5):1591;1976
Science 204(4393):624;1979
Z Naturforsch (C) 27(3):263;1972
Indexing Information
Nitric Oxide
Nitric Oxide Synthase
Date of Entry
1972/01/01
Revision Date
2018/09/24
sapropterin Preferred
5,6,7,8-tetrahydrodictyopterin Narrower
5,6,7,8-tetrahydrobiopterin, (S-(R*,S*))-isomer Narrower
D-threo-tetrahydrobiopterin Narrower
sapropterin dihydrochloride Narrower
kuvan Narrower
2,4,5-trihydroxybutyrophenone Related
6R-L-erythro-5,6,7,8-tetrahydrobiopterin Narrower
5,6,7,8-tetrahydrobiopterin Broader
5,6,7,8-erythro-tetrahydrobiopterin Narrower
tetrahydro-6-biopterin Narrower
5,6,7,8-tetrahydro-L-erythrobiopterin Narrower
phenylalanine hydroxylase cofactor Related
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