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trilostane
MeSH Supplementary Concept Data 2025
Details
Concepts
MeSH Supplementary
trilostane
Unique ID
C009954
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C009954
Entry Term(s)
4alpha,5-epoxy-17beta-hydroxy-3-oxoandrostane-2-carbonitrile
Modrenal
WIN 24,540
Pharm Action
Abortifacient Agents, Steroidal
Antineoplastic Agents
Enzyme Inhibitors
Registry Numbers
L0FPV48Q5R
0
Related Numbers
13647-35-3
Previous Indexing
*ANDROSTANES (75-80)
*ANDROSTANOLS (80-82)
NITRILES (75-82)
Heading Mapped to
Dihydrotestosterone
/
analogs & derivatives
Frequency
321
Note
inhibits conversion of pregnenolone to progesterone; adrenal blocking agent used in treatment of Cushing's syndrome
Source
Endocrinology 103(4):1411;1978
Endocrinology 97(1):136;1975
Fertil Steril 1979;32(4):464
J Endocrinol 76:293;1978
Steroids 32(2):257;1978
Indexing Information
Oxidative Phosphorylation Coupling Factors
3-Hydroxysteroid Dehydrogenases
Date of Entry
1975/01/01
Revision Date
2015/09/27
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trilostane
Preferred
Concept UI
M0055078
Registry Numbers
L0FPV48Q5R
Related Numbers
13647-35-3
Terms
trilostane
Preferred Term
Term UI
T085081
Date
01/01/1955
LexicalTag
NON
ThesaurusID
4alpha,5-epoxy-17beta-hydroxy-3-oxoandrostane-2-carbonitrile
Term UI
T085079
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (1975)
WIN 24,540
Narrower
Concept UI
M0055077
Registry Numbers
0
Terms
WIN 24,540
Preferred Term
Term UI
T085080
Date
01/01/1955
LexicalTag
LAB
ThesaurusID
NLM (1975)
Modrenal
Narrower
Concept UI
M0476902
Registry Numbers
0
Terms
Modrenal
Preferred Term
Term UI
T621648
Date
12/03/2004
LexicalTag
TRD
ThesaurusID
UK
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