MeSH Browser

MeSH Supplementary: gabaculine
Unique ID: C012987
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C012987
Entry Term(s): 3-amino-2,3-dihydrobenzoic acid; gabaculin; gabaculine hydrochloride; gabaculine hydrochloride, (+-)-isomer; gabaculine, (+-)-isomer; gabaculine, (-)-isomer
Pharm Action: Enzyme Inhibitors
Registry Numbers: 3F3ENU341O; 59556-17-1; 59556-18-2; 59556-29-5; 74032-85-2
Related Numbers: 59556-17-1; 59556-18-2; 59556-29-5; 74032-85-2; 87980-11-8
CAS Type 1 Name: 5-amino-1,3-cyclohexadienylcarboxylic acid
Previous Indexing: CYCLOHEXYLAMINES (77-82)
Heading Mapped to: *Cyclohexanecarboxylic Acids
Frequency: 130
Note: potent inhibitor of aminobutyrate aminotransferase from Streptomyces toyocaensis.; also inhibits a variety of PLP-dependent aminotransferases; structure; RN given refers to cpd without isomeric designation
Source: Biochem Biophys Res Commun 76(4):1276;1977; Eur J Pharmacol 50(3):243;1978; J Am Chem Soc 99(15):5141;1977; J Biol Chem 1980;255(2):428; J Biol Chem 253(20):7431;1978; Life Sci 20:1291;1977; Naunyn-Schmiedeberg's Arch Pharm 305(3):219;1978; Neurosci Lett 1979;14(2,3):327
Indexing Information: Transaminases
Date Introduced: 1977/01/01
Last Updated: 2017/06/23

gabaculine MeSH Supplementary Concept Data 2026