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benzphetamine N-demethylase MeSH Supplementary Concept Data 2025


MeSH Supplementary
benzphetamine N-demethylase
Unique ID
C019781
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C019781
Entry Term(s)
P450LgM2
benzphetamine demethylase
cytochrome P-450 CYP2B (lung microsomal)
cytochrome P-450 CYPLgM2
cytochrome P450LgM2
Registry Numbers
EC 1.14.14.1
EC 1.14.14.1
Related Numbers
EC 1.14.14.1
Previous Indexing
BENZPHETAMINE (74-81)
*OXIDOREDUCTASES (74-77)
Heading Mapped to
*Cytochrome P-450 Enzyme System
*Oxidoreductases, N-Demethylating
Frequency
131
Note
benzphetamine N-demethylase, P-450 isozymes encoded by a number of genes from the CYP2 and CYP3 families; CYPLgM2 is a nonspecific hydroxylase from lung tissue of several species including sheep, cows, rabbits, rats, and humans; members of the cytochrome P-450 CYP2B subfamily
Source
Acta Biol Med Ger 1979;38(1):11
Arch Environ Health 34(6):400;1979
Biochem Biophys Res Commun 1979;91(3):747
Biochem Mol Biol Int 1995 Dec;37(6):1121-6
Biochem Pharmacol 25(19):2187;1976
Biochim Biophys Acta 509:326;1978
Cancer Res 34(9):2196;1974
Date of Entry
1974/01/01
Revision Date
2002/10/23
benzphetamine N-demethylase Preferred
cytochrome P-450 CYP2B (lung microsomal) Narrower
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