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MK 761 MeSH Supplementary Concept Data 2024


MeSH Supplementary
MK 761
Unique ID
C021276
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C021276
Entry Term(s)
(S)-2-(3-tert-butylamino-2-hydroxypropoxy)-3-cyanopyridine
2-(3-tert-butylamino-2-hydroxypropoxy)-3-cyanopyridine
MK 761, (R)-isomer
MK 761, monohydrochloride
MK 761, monohydrochloride, (R)-isomer
MK 761, monohydrochloride, (S)-isomer
MK-761
Registry Number
65321-41-7
Related Numbers
60559-92-4
71677-55-9
71677-56-0
CAS Type 1 Name
3-pyridinecarbonitrile, 2-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-, (S)-
Heading Mapped to
*Pyridines
Frequency
9
Note
RN given refers to parent cpd(S)-isomer; MK-761 refers to mono-HCl; structure in sixth source
Source
Drug Metab Dispos 1980;8(3):163
Experientia 1979;35(12):1634
J Med Chem 1980;23(1):65
J Pharm Sci 1979;68(12):1559
J Pharmacol Exp Ther 211(1):195;1979
J Pharmacol Exp Ther 211(1):200;1979
Date of Entry
1980/01/01
Revision Date
2000/08/28
MK 761 Preferred
MK 761, monohydrochloride Narrower
(S)-2-(3-tert-butylamino-2-hydroxypropoxy)-3-cyanopyridine Broader
MK 761, (R)-isomer Narrower
2-(3-tert-butylamino-2-hydroxypropoxy)-3-cyanopyridine Broader
MK 761, monohydrochloride, (R)-isomer Narrower
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