NLM Logo

LY 117018 MeSH Supplementary Concept Data 2024


MeSH Supplementary
LY 117018
Unique ID
C025430
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C025430
Entry Term(s)
6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl 4-(2-(1-pyrrolidinyl)ethoxy) phenyl ketone
LY 139478
LY-117018
LY-139478
LY117018
Lilly 117018
Pharm Action
Estrogen Antagonists
Selective Estrogen Receptor Modulators
Registry Number
63676-25-5
CAS Type 1 Name
Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-
Heading Mapped to
*Pyrrolidines
*Thiophenes
Frequency
101
Note
from Eli Lilly; less estrogenic & more estrogen-antagonistic than tamoxifen & trioxifene in rats & mice; LY 139478 is the HCl salt of LY 117018; LY 139478 is an estrogen agonist; structure in first source; a raloxifene analog
Source
Life Sci 1980;26(17):1453
Date of Entry
1980/07/25
Revision Date
2001/07/18
LY 117018 Preferred
LY 139478 Related
6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl 4-(2-(1-pyrrolidinyl)ethoxy) phenyl ketone Broader
page delivered in 0.01s