MeSH Browser

MeSH Supplementary: LY 117018
Unique ID: C025430
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C025430
Entry Term(s): 6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl 4-(2-(1-pyrrolidinyl)ethoxy) phenyl ketone; LY 139478; LY-117018; LY-139478; LY117018; Lilly 117018
Pharm Action: Estrogen Antagonists
Selective Estrogen Receptor Modulators
Registry Number: 63676-25-5
CAS Type 1 Name: Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-
Heading Mapped to: *Pyrrolidines; *Thiophenes
Frequency: 101
Note: from Eli Lilly; less estrogenic & more estrogen-antagonistic than tamoxifen & trioxifene in rats & mice; LY 139478 is the HCl salt of LY 117018; LY 139478 is an estrogen agonist; structure in first source; a raloxifene analog
Source: Life Sci 1980;26(17):1453
Date of Entry: 1980/07/25
Revision Date: 2001/07/18

LY 117018 MeSH Supplementary Concept Data 2024