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5-chlorocyclophosphamide MeSH Supplementary Concept Data 2024


MeSH Supplementary
5-chlorocyclophosphamide
Unique ID
C033253
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C033253
Entry Term(s)
2-(bis(2-chloroethyl)amino)tetrahydro-5-chloro-2H-1,3,2-oxazaphosphorine 2-oxide
cis-5-chlorocyclophosphamide
endoxan-asta
trans-5-chlorocyclophosphamide
Registry Number
0
Heading Mapped to
Cyclophosphamide / *analogs & derivatives
Frequency
4
Note
both cis- & trans-isomer have half the therapeutic index of cyclophosphamide; structure in first source
Source
J Med Chem 1981;24(12):1399
Date of Entry
1982/01/23
Revision Date
1986/12/12
5-chlorocyclophosphamide Preferred
endoxan-asta Narrower
cis-5-chlorocyclophosphamide Narrower
trans-5-chlorocyclophosphamide Narrower
2-(bis(2-chloroethyl)amino)tetrahydro-5-chloro-2H-1,3,2-oxazaphosphorine 2-oxide Narrower
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