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tirilazad MeSH Supplementary Concept Data 2025


MeSH Supplementary
tirilazad
Unique ID
C053355
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C053355
Entry Term(s)
21-(4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methylpregna-1,4,9(11)-triene-3,20-dione monomethane sulfonate
Freedox
U 74006F
U-74006
U-74006F
U74006F
pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methyl-, (16alpha)-, monomethanesulfonate
tirilazad mesylate
tirilazad mesylate hydrate
Pharm Action
Antioxidants
Neuroprotective Agents
Registry Numbers
YD064E883I
0
HXS259UWKW
Related Numbers
110101-66-1
110101-67-2
111793-42-1
HXS259UWKW
Heading Mapped to
*Pregnatrienes
Frequency
360
Note
a lazaroid; potent inhibitor of iron-dependent lipid peroxidation; has shown excellent activity in in vivo models of experimental central nervous system trauma & ischemia; structure given in first source; tradename Freedox
Source
J Biol Chem 1987;262(22):10438
Date of Entry
1987/09/14
Revision Date
2018/10/15
tirilazad Preferred
Freedox Narrower
U 74006F Narrower
tirilazad mesylate hydrate Narrower
pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methyl-, (16alpha)-, monomethanesulfonate Narrower
U-74006 Narrower
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