MeSH Browser

MeSH Heading: Neuroprotective Agents
Tree Number(s): D27.505.696.706.548; D27.505.954.427.575
Unique ID: D018696
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018696
Annotation: note entry term NEUROPROTECTIVE EFFECT: use only for the neuroprotective effect of a chemical substance
Scope Note: Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
Entry Term(s): Neuroprotectant; Neuroprotectants; Neuroprotective Agent; Neuroprotective Drug; Neuroprotective Drugs; Neuroprotective Effect; Neuroprotective Effects; Neurotrophic Agents; Neurotrophic Drugs
Registry Numbers: 0
Public MeSH Note: 95
History Note: 95
Date Introduced: 1995/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0028008
Registry Numbers: 0
Scope Note: Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
Terms: Neuroprotective Agents Preferred Term
Term UI T055669
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1995); Neuroprotectant
Term UI T000998922
Date11/21/2019
LexicalTag NON
ThesaurusID NLM (2021); Neuroprotectants
Term UI T055671
Date04/06/1994
LexicalTag NON
ThesaurusID NLM (1995); Neuroprotective Agent
Term UI T000998921
Date11/21/2019
LexicalTag NON
ThesaurusID NLM (2021); Neuroprotective Drug
Term UI T000998923
Date11/21/2019
LexicalTag NON
ThesaurusID NLM (2021); Neuroprotective Drugs
Term UI T055670
Date04/06/1994
LexicalTag NON
ThesaurusID NLM (1995)

Neuroprotective Agents MeSH Descriptor Data 2026