MeSH Browser

MeSH Supplementary: immunophilin ligand 506BD
Unique ID: C066205
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C066205
Registry Number: 0
Heading Mapped to: *Cyclohexanols; *Pyrans
Frequency: 6
Note: nonnatural immunophilin ligand which contains only the common structural elements of FK 506 & rapamycin; a high affinity ligand of FK 506-binding protein & potent inhibitor of FKBP rotamase activity; does not interfere with T cell activation, but blocks suppressive effects of FK 506 & rapamycin; structure given in first source
Source: Science 1990;250(4980):556
Date of Entry: 1990/11/26
Revision Date: 1991/04/12

immunophilin ligand 506BD MeSH Supplementary Concept Data 2024