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RB 101 MeSH Supplementary Concept Data 2024


MeSH Supplementary
RB 101
Unique ID
C074024
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C074024
Entry Term(s)
N-(2-benzyl-3-((2-amino-4-methylthio)butyl dithio)-1-oxopropyl)phenylalanine benzyl ester
RB-101
RB101
Pharm Action
Analgesics
Enzyme Inhibitors
Registry Number
135949-60-9
CAS Type 1 Name
L-Phenylalanine, N-(2-(((2-amino-4-(methylthio)butyl)dithio)methyl)-1-oxo-3-phenylpropyl)-, phenylmethyl ester
Heading Mapped to
*Disulfides
Phenylalanine / *analogs & derivatives
Frequency
57
Note
structure given in first source; inhibits enkephalinase and aminopeptidases; biologically cleaved at disulfide to produce inhibitors of both aminopeptidase N and neutral endopeptidase
Source
J Pharmacol Exp Ther 1992 Apr;261(1):181-90
Indexing Information
Prodrugs
Date of Entry
1992/05/10
Revision Date
2005/07/29
RB 101 Preferred
N-(2-benzyl-3-((2-amino-4-methylthio)butyl dithio)-1-oxopropyl)phenylalanine benzyl ester Broader
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