MeSH Browser

MeSH Supplementary: FK 453
Unique ID: C077100
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C077100
Entry Term(s): (+)-(R)-(1-(E)-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)acryl)-2-piperidine ethanol; FR 113452; FR 113453; FR113452; FR113453
Registry Numbers: 121524-18-3
CAS Type 1 Name: 2-Piperidineethanol, 1-(1-oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-propenyl)-, (R-(E))-
Heading Mapped to: *Pyrazoles; *Pyridines
Frequency: 15
Note: adenosine A1 receptor antagonist; structure given in first source; a new antihypertensive agent with diuretic action in isolated rabbit aorta; FR113452 is the S-(-) enantiomer of FK 453
Source: Pharmacology 1992;44(4):206-14
Date of Entry: 1992/11/02
Revision Date: 2001/01/11

FK 453 MeSH Supplementary Concept Data 2025