MeSH Browser

MeSH Supplementary: MK 0591
Unique ID: C078266
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C078266
Entry Term(s): 1H-Indole-2-propanoic acid, 1-((4-chlorophenyl)methyl)-3-((1,1-dimethylethyl)thio)-alpha,alpha-dimethyl-5-(2-quinolinylmethoxy)-; 3-(1-(4-chlorobenzyl-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl))-2,2-dimethyl propanoic acid; L 686708; L-686,708; MK 591; MK-0591; MK-591; MK591 compound
Pharm Action: 5-Lipoxygenase-Activating Protein Inhibitors
Registry Numbers: 136668-42-3; 0
Related Numbers: 321US0I5R6
Heading Mapped to: *Indoles; *Quinolines
Frequency: 48
Note: structure given in first source; MK 0591 was previously L-686,708; inhibits leukotriene biosynthesis by inhibiting 5-lipoxygenase activating protein
Source: Can J Physiol Pharmacol 1992 Jun;70(6):808-13
Date of Entry: 1992/12/22
Revision Date: 2018/12/06

Concept UI: M0209855
Registry Numbers: 136668-42-3
Related Numbers: 321US0I5R6
Terms: MK 0591 Preferred Term
Term UI T239860
Date01/01/1955
LexicalTag LAB
ThesaurusID NLM (1992); MK-591
Term UI T239859
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (1992); MK 591
Term UI T239857
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (1992); MK-0591
Term UI T239858
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (1992); MK591 compound
Term UI T000893663
Date01/14/2016
LexicalTag NON
ThesaurusID NLM (2016)

MK 0591 MeSH Supplementary Concept Data 2025