was heading 1963-95; use ANTIRETICULAR CYTOTOXIC SERUM (NM) to search ANTIRETICULAR CYTOTOXIC SERUM 1980-95, use IMMUNE SERA to search ANTIRETICULAR CYTOTOXIC SERUM 1966-79; an obsolete term for an antiserum produced by immunizing horses with human spleen and bone marrow cells; it is said to have a stimulating effect on the reticuloendothelial system in small doses and a cytotoxic effect in large doses