MeSH Browser

MeSH Supplementary: Y 27632
Unique ID: C108830
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C108830
Entry Term(s): N-(4-pyridyl)-4-(1-aminoethyl)cyclohexanecarboxamide; Y 27632, (4(R)-trans)-isomer; Y 27632, (4(S)-trans)-isomer; Y 27632, (trans)-isomer; Y 27632, dihydrochloride, (4(R)-trans)-isomer; Y-27632; Y27632
Pharm Action: Antihypertensive Agents
Enzyme Inhibitors
Muscle Relaxants, Central
Registry Number: 138381-45-0
Related Numbers: 129758-26-5; 129830-38-2; 146986-50-7; 146986-51-8
Heading Mapped to: *Amides; *Pyridines
Frequency: 1885
Note: RN given for di-HCl salt; inhibits Rho-associated protein kinase; inhibits calcium sensitization to affect smooth muscle relaxation; structure in first source
Source: Nature 1997 Oct 30;389(6654):990-4
Date of Entry: 1997/11/17
Revision Date: 2006/05/08

Y 27632 MeSH Supplementary Concept Data 2024