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lonafarnib MeSH Supplementary Concept Data 2022


MeSH Supplementary
lonafarnib
Unique ID
C115354
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C115354
Entry Term(s)
(+)4-(2-(4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-yl)-1-piperidinyl)-2-oxoethyl)-1-piperidinecarboxamide
4-(2-(4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo-(5,6)-cyclohepta(1,2-b)-pyridin-11(R)-yl)-1-piperidinyl)-2-oxo-ethyl)-1-piperidinecarboxamide
SCH 66336
SCH66336
zokinvy
Pharm Action
Enzyme Inhibitors
Registry Number
IOW153004F
Related Numbers
193275-84-2
CAS Type 1 Name
1-Piperidinecarboxamide, 4(2-(4-(11R-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridine-11-yl)-1-piperidinyl)-2-oxoethyl)-
Heading Mapped to
*Piperidines
*Pyridines
Frequency
191
Note
inhibitor of farnesyl protein transferase; structure in first source
Source
Cancer Res 1998 Nov 1;58(21):4947-56
Date of Entry
1998/11/17
Revision Date
2021/07/20
lonafarnib Preferred
(+)4-(2-(4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-yl)-1-piperidinyl)-2-oxoethyl)-1-piperidinecarboxamide Broader
zokinvy Narrower
SCH66336 Narrower
4-(2-(4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo-(5,6)-cyclohepta(1,2-b)-pyridin-11(R)-yl)-1-piperidinyl)-2-oxo-ethyl)-1-piperidinecarboxamide Broader
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