MeSH Browser

MeSH Supplementary: pimecrolimus
Unique ID: C117268
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C117268
Entry Term(s): 33-epi-chloro-33-desoxyascomycin; ASM 981; Elidel; SDZ ASM 981; SDZ-ASM-981
Pharm Action: Anti-Inflammatory Agents, Non-Steroidal
Dermatologic Agents
Immunosuppressive Agents
Calcineurin Inhibitors
Registry Number: 7KYV510875
Heading Mapped to: Tacrolimus / *analogs & derivatives
Frequency: 662
Note: an ascomycin derivative; mechanism of action involves calcineurin inhibition, blockage of T cell activation, blocking signal transduction pathways in T cells, and inhibition of the synthesis of inflammatory cytokines, specifically Th1- and Th2-type cytokines
Source: J Pharmacol Exp Ther 1999 Feb;288(2):653-9
Indexing Information: Peptidylprolyl Isomerase
Date of Entry: 1999/02/19
Revision Date: 2016/12/22

pimecrolimus MeSH Supplementary Concept Data 2024