MeSH Browser

MeSH Supplementary: PDZ-binding kinase
Unique ID: C409022
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C409022
Entry Term(s): MAPKK-like protein kinase; Nori-3 protein, human; PBK enzyme; PBK protein, human; PDZ binding kinase, human; T-LAK cell-originated protein kinase, human; TOPK protein, human; lymphokine-activated killer T-cell-originated protein kinase, human; spermatogenesis-related protein kinase
Registry Numbers: EC 2.7.12.2; EC 2.7.12.2
Related Numbers: EC 2.7.12.2; T312O1GF3M
Previous Indexing: *PROTEIN-SERINE-THREONINE KINASES (2000-2012)
Heading Mapped to: *Mitogen-Activated Protein Kinase Kinases
Frequency: 151
Note: a mitotic kinase that binds the PDZ2 domain of human Dlg protein (hDlg); phosphorylated during mitosis; found to increase highly in proliferative malignant cells, upregulated in Burkitt's lymphom and during normal fetal development; amino acid sequence in first source; GenBank AF189722
Source: Proc Natl Acad Sci U S A 2000 May 9;97(10):5167-72
Date of Entry: 2000/06/09
Revision Date: 2018/11/28

Concept UI: M0363871
Registry Numbers: EC 2.7.12.2
Related Numbers: EC 2.7.12.2; T312O1GF3M
Terms: PDZ-binding kinase Preferred Term
Term UI T416410
Date06/09/2000
LexicalTag NON
ThesaurusID NLM (2000); MAPKK-like protein kinase
Term UI T651669
Date09/15/2005
LexicalTag NON
ThesaurusID NLM (2005); PBK enzyme
Term UI T416411
Date06/09/2000
LexicalTag NON
ThesaurusID NLM (2000); spermatogenesis-related protein kinase
Term UI T468294
Date10/30/2001
LexicalTag NON
ThesaurusID NLM (2001)

PDZ-binding kinase MeSH Supplementary Concept Data 2025