MeSH Browser

MeSH Supplementary: AML1-MDS1-EVI1 fusion protein, human
Unique ID: C460199
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C460199
Entry Term(s): AML1-MDS1-EVI1 protein, human
Registry Numbers: 0
Heading Mapped to: *Repressor Proteins; *Oncogene Proteins, Fusion; *Core Binding Factor Alpha 2 Subunit
Frequency: 6
Note: leukemia-associated fusion gene AML1/MDS1/EVI1 (AME) encodes a chimeric transcription factor that results from the (3;21)(q26;q22) translocation; this translocation is observed in patients with therapy-related myelodysplastic syndrome (MDS), with chronic myelogenous leukemia during the blast crisis (CML-BC), and with de novo or therapy-related acute myeloid leukemia (AML)
Source: Oncogene 2002 May 9;21(20):3232-40
Date of Entry: 2002/07/22
Revision Date: 2014/09/24

AML1-MDS1-EVI1 fusion protein, human MeSH Supplementary Concept Data 2025